Major Uses

Cefovecin Sodium is an antibiotic most commonly used for the treatment of bacterial infections. This drug may be used in the treatment of skin infections, respiratory tract infections, bone and joint infections, itra-abdominal infections, and Septicemia in both dogs and cats. In dogs, Cefovecin Sodium is most effective in treating skin infections caused by Straphylococcus intermedius and Streptoccocus canis. In cats, Cefovecin Sodium is most effective in treating skin infections caused by Pasteurella multocida. Cefovecin Sodium is not effective in treating infections caused by viruses, parasites, fungi, or mites.

Common Precautions

Side effects most commonly associated with Cefovecin Sodium are vomiting, diarrhea, lethargy, and decreased appetite. It is not uncommon for cats to become hyperactive or inappropriately urinate. High doses of Cefovecin Sodium can cause nephrotoxicity, neurotoxicity, hepatitis, and changes in the blood leukogram and thrombocytopenia. The use of this drug in pregnant animals should be discussed with a veterinarian.

Cefovecin Sodium should not be administered in animals with a known allergy or hypersensitivity to the drug. Cefovecin Sodium may interact with other medications. This should be discussed with a veterinarian. Emergency veterinary care should be sought if an animal experiences any unusual symptoms.


Cefovecin Sodium powder and reconstituted solution should be stored in the original container. It should be kept refrigerated.


Cefovecin Sodium is available in powder form in a 10 mL 800 milligram bottle. It is reconstituted with 10 mL of sterile water for injection and is then 80 mg/ml.

A typical dose range for Cefovecin Sodium in dogs is 8 mg/kg SC once to treat skin infections caused by S. intermedius or S. canis. Dose may vary in different species, when the drug is given by a different route or concurrently with other medications, and with regards to a patient's age, breed, and health status. A veterinarian's dosing instructions and/or those printed on the medication label should be followed closely.

Repeat administration depends on the condition being treated, response to the medication, and the development of any adverse effects. A veterinarian will make this determination based on a pet's response to initial treatment. Two doses of Cefovecin Sodium should not be administered at the same time.

This information is for general reference only and should not be used for the diagnosis or treatment of any condition of your pet. It's intended as a general reference, this information may not include all possible uses, precautions, directions, reactions (including allergic), drug interactions, or withdrawal times. Always consult your local veterinarian and have your pet examined for any advice concerning the diagnosis and treatment of your pet, including which products and doses are most appropriate. Any trademarks are the property of their respective owners. VetDepot is not a pharmacy. All prescription products are dispensed by our Pharmacy Partner. Article last updated 2/2014.