Major Uses

Cefpodoxime Proxetil is an antibiotic that is most commonly used to treat bacterial infections in dogs and cats. It is most effective in the treatment of skin infections, wound infections, bone infections, bladder infections, and pneumonia. Cefpodoxime Proxetil is an antibiotic of the cephalosporin class and is effective against bacterial strains such as Staphyloccoccus intermedius, Staphlyococcus aureus, Streptoccus canis, Escherichia coli, Pasteurella multicida, and Proteus mirabilis. This drug is not effective in treating infections caused by viruses, parasites, mites, or fungi.

Common Precautions

Side effects most commonly associated with Cefpodoxime Proxetil are stomach upset and a decreased appetite.

Cefpodoxime Proxetil should not be administered in animals with a known allergy or hypersensitivity to the drug. Cefpodoxime Proxetil may interact with other medications including Antacids. This should be discussed with a veterinarian. Cefpodoxime Proxetil should be used with caution in animals that are pregnant or lactating. Emergency veterinary care should be sought if an animal experiences any unusual symptoms.


Cefpodoxime Proxetil capsules and un-reconstituted powder should be stored in a tight container at room temperature. After reconstitution, the oral suspension should be refrigerated and discarded after 14 days.


Cefpodoxime Proxetil is available in 100 mg and 200 mg capsules as well as an un-reconstituted powder.

A typical dose range for Cefpodoxime Proxetil in dogs is 5-10 mg/kg PO once daily for 5-7 days for the treatment of skin infections. Dose may vary in different species, when the drug is given by a different route or concurrently with other medications, and with regards to a patient's age, breed, and health status. A veterinarian's dosing instructions and/or those printed on the medication label should be followed closely.

If a dose is missed, it should be administered as soon as possible. If it is almost time for the subsequent dose, the missed dose should be skipped and the regular administration schedule resumed. Two doses of Cefpodoxime Proxetil should not be administered at the same time.

This information is for general reference only and should not be used for the diagnosis or treatment of any condition of your pet. It's intended as a general reference, this information may not include all possible uses, precautions, directions, reactions (including allergic), drug interactions, or withdrawal times. Always consult your local veterinarian and have your pet examined for any advice concerning the diagnosis and treatment of your pet, including which products and doses are most appropriate. Any trademarks are the property of their respective owners. VetDepot is not a pharmacy. All prescription products are dispensed by our Pharmacy Partner. Article last updated 2/2014.