Generic Drug Name: Deslorelin
Other Common Names: Ovuplant
Deslorelin is a synthetic GnRH analog that is used to induce and time ovulation in estrual mares by increasing levels of endogenous luteinizing hormones. Desorelin can be used to help stabilize high risk pregnancies as well. This drug is also used to control reproduction in dogs and, in some cases, can even be used as a form of contraception.
Side effects most commonly associated with Deslorelin are swelling at either the IM injection site, or the implantation site. Skin sensitivity and elevated skin temperature are not uncommon and usually resolve within about 5 days.
Deslorelin should not be used in animals with a hypersensitivity to the drug. This drug should not be administered intravenously. Hives and moderate tremors may be a sign of drug toxicity. A veterinarian should be contacted if an animal experiences any unusual symptoms or behaviors.
Deslorelin implants and injectable solution should be kept refrigerated.
Deslorelin is available as an injectable solution as well as an implant.
A typical dose range for Deslorelin is a 4.7 mg implant used every 6 months for use as a contraceptive in dogs. Dose may vary in different species, when the drug is given by a different route or concurrently with other medications, and with regards to a patient's age, breed, and health status. A veterinarian's dosing instructions and/or those printed on the medication label should be followed closely.
If a dose is missed, it should be administered as soon as possible. If it is almost time for the subsequent dose, the missed dose should be skipped and the regular administration schedule resumed. Two implants or doses of Deslorelin should not be administered at the same time.