Major Uses

Deslorelin is a synthetic GnRH analog that is used to induce and time ovulation in estrual mares by increasing levels of endogenous luteinizing hormones. Desorelin can be used to help stabilize high risk pregnancies as well. This drug is also used to control reproduction in dogs and, in some cases, can even be used as a form of contraception.

Common Precautions

Side effects most commonly associated with Deslorelin are swelling at either the IM injection site, or the implantation site. Skin sensitivity and elevated skin temperature are not uncommon and usually resolve within about 5 days.

Deslorelin should not be used in animals with a hypersensitivity to the drug. This drug should not be administered intravenously. Hives and moderate tremors may be a sign of drug toxicity. A veterinarian should be contacted if an animal experiences any unusual symptoms or behaviors.


Deslorelin implants and injectable solution should be kept refrigerated.


Deslorelin is available as an injectable solution as well as an implant.

A typical dose range for Deslorelin is a 4.7 mg implant used every 6 months for use as a contraceptive in dogs. Dose may vary in different species, when the drug is given by a different route or concurrently with other medications, and with regards to a patient's age, breed, and health status. A veterinarian's dosing instructions and/or those printed on the medication label should be followed closely.

If a dose is missed, it should be administered as soon as possible. If it is almost time for the subsequent dose, the missed dose should be skipped and the regular administration schedule resumed. Two implants or doses of Deslorelin should not be administered at the same time.

This information is for general reference only and should not be used for the diagnosis or treatment of any condition of your pet. It's intended as a general reference, this information may not include all possible uses, precautions, directions, reactions (including allergic), drug interactions, or withdrawal times. Always consult your local veterinarian and have your pet examined for any advice concerning the diagnosis and treatment of your pet, including which products and doses are most appropriate. Any trademarks are the property of their respective owners. VetDepot is not a pharmacy. All prescription products are dispensed by our Pharmacy Partner. Article last updated 2/2014.