Major Uses

Epsiprantel is an anthelmintic used to treat tapeworms in cats and dogs. This medication likely works by disrupting the regulation of calcium and other cations to cause tetanic muscle contraction and paralysis in parasites. It is only very minimally absorbed following oral administration.

Epsiprantel is effective against Dipylidium caninum in cats and dogs, Taenia taeniaeformis in cats, and Taenia pisiformis in dogs.

Common Precautions

No side effects have been reported in animals being treated with epsiprantel. Vomiting and diarrhea are possible, but unlikely.

It is not known if epsiprantel is safe for use during pregnancy or lactation. Safety has not been determined in breeding animals. Treating kittens and puppies less than 7 weeks of age with epsiprantel is not recommended. This drug is not for human use. No drug interactions have been reported.

Epsiprantel should not be used in animals with a known allergy or hypersensitivity to the drug.

Because epsiprantel is so minimally absorbed, overdose is very unlikely. Extremely high doses may cause trembling and vomiting in kittens and cats. Symptoms of overdose in puppies and dogs may cause increased alkaline phosphatase, decreased lymphocyte count, slight proteinuria, vomiting, and decreased total white cell count. Any known or suspected overdose should be reported to a veterinarian right away.


Epsiprantel should be stored between 59 86 degrees Fahrenheit, in a tightly sealed container, out of the reach of children and animals.


Epsiprantel is available in tablet form. The typical recommended dose of epsiprantel in cats is 1.25 mg/lb of body weight. In dogs, the recommended dose is 2.5 mg/lb of body weight. Fasting is not recommended. Doses may vary in different species, when the drug is given by a different route or concurrently with other medications, and with regards to a patient's age, breed, and health status. A veterinarian's dosing instructions and/or those printed on the medication label should be followed closely.

This medication is generally used as a single dose. Correction of partial or incomplete doses should be handled by a veterinarian.

This information is for general reference only and should not be used for the diagnosis or treatment of any condition of your pet. It's intended as a general reference, this information may not include all possible uses, precautions, directions, reactions (including allergic), drug interactions, or withdrawal times. Always consult your local veterinarian and have your pet examined for any advice concerning the diagnosis and treatment of your pet, including which products and doses are most appropriate. Any trademarks are the property of their respective owners. VetDepot is not a pharmacy. All prescription products are dispensed by our Pharmacy Partner. Article last updated 2/2014.