Major Uses

Firocoxib is used primarily in dogs and horses to relieve pain and reduce inflammation caused by osteoarthritis. It is also used to control post-operative pain and inflammation caused by orthopedic surgery.

Common Precautions

Firocoxib has been known to cause upset stomach and stomach ulcers in animals, which may result in vomiting, diarrhea, loss of appetite, and blood in the stool. This drug may also affect the kidney, symptoms of which are excessive thirst and urination, as well as changes in urine smell or color. Symptoms related to the liver are yellowing of the eyes, skin, and gums. Symptoms related to an allergic reaction to the drug may include facial swelling, hives, diarrhea, scratching, vomiting, seizures, shock, pale gums, cold limbs, or even coma.

Firocoxib should not be used in horses less than a year old, as safety has not yet been determined. It should also not be taken by puppies under the age of 7 months old, as high doses in these animals can cause increased rates of hepatic fatty changes, which can be fatal.

Firocoxib should not be used in animals with a known allergy or hypersensitivity to the drug. A Veterinarian should be contacted immediately if an overdose is suspected, the symptoms of which are vomiting, diarrhea, blood in stool, constipation, jaundice, seizure, changes in urine color and smell, and even behavioral changes.


Firocoxib must be stored at room temperature in a light-resistant, childproof container, and placed where it will not be exposed to high heat.


Firocoxib is usually packaged as a flavored, chewable tablet. It should be administered once daily, with or without food. A typical dose for dogs is 5 mg/kg (2.27 mg/lb), which should amount to half a tablet. A typical dose for horses is 0.1 mg/kg (0.045 mg/lb) once daily for up to 14 days. If a dose is missed, it should be given immediately. If the next scheduled dose is close, the missed dose should be skipped and the scheduled dose administered. At this point, the user should continue on with the normal schedule. Never should two doses be given at the same time.

Doses may vary in different species, when the drug is given by a different route or concurrently with other medications, and with regards to a patient's age, breed, and health status. A veterinarian's dosing instructions and/or those printed on the medication label should be followed closely.

This information is for general reference only and should not be used for the diagnosis or treatment of any condition of your pet. It's intended as a general reference, this information may not include all possible uses, precautions, directions, reactions (including allergic), drug interactions, or withdrawal times. Always consult your local veterinarian and have your pet examined for any advice concerning the diagnosis and treatment of your pet, including which products and doses are most appropriate. Any trademarks are the property of their respective owners. VetDepot is not a pharmacy. All prescription products are dispensed by our Pharmacy Partner. Article last updated 2/2014.